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KMID : 0363220130510070531
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Korean Journal of Dermatology
2013 Volume.51 No. 7 p.531 ~ p.535
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A Case of Histiocytoid Sweet Syndrome Developed in the Patient with Pure White Cell Aplasia
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Lee Hye-Young
Kim Jun-Ki
Lee Ji-Yeoun
Kim Mi-Kyeong
Yoon Tae-Young
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Abstract
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Histiocytoid Sweet syndrome (HSS) is a rare inflammatory disease that has recently been described as a variant of Sweet syndrome. Histopathologically, HSS is characterized by papillary dermal edema with infiltration of histiocytoid cells into the upper dermis. The histiocytoid cells are easily misinterpreted as histiocyte, but in fact, they are immature myeloid cells. To demonstrate cells of myeloid lineage, specific staining must be performed, such as myeloperoxidase (MPO). To date, there are several HSS cases associated with hematological malignancy, drugs, and chronic inflammatory diseases. But, in Korea, only one case has been reported so far. Herein, we report a case of HSS developed in the patient with pure white cell aplasia and review the relevant literature.
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KEYWORD
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Histiocytoid Sweet syndrome, Myeloperoxidase
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